Assignment: Pharmacotherapy for Cutaneous Candidiasis

Assignment: Pharmacotherapy for Cutaneous Candidiasis

Assignment: Pharmacotherapy for Cutaneous Candidiasis

Describe the treatment of cutaneous candida including first-line medication selection, contraindications, ADR’s, monitoring, and patient education. please use professional articles with DOIs

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Pharmacotherapy for Cutaneous Candidiasis

Candida is the yeast-type of fungus that causes the condition known as candidiasis. The most common species of Candida is Candida albicans and it is a natural flora living on the skin and inside the body in areas such as the vagina, the mouth, the throat, and the gastrointestinal tract. Under these natural conditions it causes no disease or symptoms. However, when the person’s immunity is compromised or the delicate balance of the symbiotic existence of the microbe is disturbed; infection and symptoms occur (CDC, 2020; Hammer & McPhee, 2018). Predisposing conditions include diabetes, HIV, poor hygiene, and obesity amongst others (Armstrong et al., 2016). The purpose of this paper is t describe the treatment of cutaneous candidiasis.

The Treatment of Cutaneous Candidiasis

The first-line of treatment for cutaneous candidiasis involves the use of topical antifungal agents. According to Taudorf et al. (2019), clotrimazole (Lotrimin), nystatin, and miconazole (Micatin) are among the topical agents that have scientific evidence backing their efficacy as first-line treatments for cutaneous Candida.

A major contraindication to the use of topical antifungals is a history of sensitivity and allergy. The common side effects and adverse drug reactions include tenderness, swelling, redness, irritation, stinging sensation, and a burning sensation amongst others. Monitoring should be for the possible adverse effects such as burning, rash, and local irritation. The patient should also be monitored for medication compliance to ascertain therapeutic effectiveness. Patient education should be on the side effects and the need for medication adherence for best outcomes.

Conclusion

Candida albicans is the most common type of Candida. It is a normal flora of the human body but can cause candidiasis in the event of a lapse in immunity. The first-line treatment for cutaneous candidiasis is the use of topical antifungals such as nystatin, clotrimazole, and miconazole.

References

Armstrong, A.W., Bukhalo, M., & Blauvelt, A. (2016). A clinician’s guide to the diagnosis and treatment of candidiasis in patients with psoriasis. American Journal of Clinical Dermatology, 17(4), 329–336. https://doi.org/10.1007/s40257-016-0206-4 

Centers for Disease Control and Prevention [CDC] (October 30, 2020). Candidiasis. https://www.cdc.gov/fungal/diseases/candidiasis/index.html#:~:text=Candidiasis%20is%20a%20fungal%20infection,vagina%2C%20without%20causing%20any%20problems.

Hammer, D.G., & McPhee, S.J. (Eds). (2018). Pathophysiology of disease: An introduction to clinical medicine, 8^th ed. McGraw-Hill Education.

Taudorf, E.H., Jemec, G.B.E., Hay, R.J., & Saunte, D.M.L. (2019). Cutaneous candidiasis – An evidence‐based review of topical and systemic treatments to inform clinical practice. Journal of the European Academy of Dermatology and Venereology, 33, 1863-1873. http://dx.doi.org/10.1111/jdv.15782