NUR 39700 Discussion: A Systematic Review of Practice Guidelines and Recommendations for Discontinuation of Cholinesterase Inhibitors in Dementia

NUR 39700 Discussion: A Systematic Review of Practice Guidelines and Recommendations for Discontinuation of Cholinesterase Inhibitors in Dementia

NUR 39700 Discussion: A Systematic Review of Practice Guidelines and Recommendations for Discontinuation of Cholinesterase Inhibitors in Dementia

EBP Guideline Related to Sexuality, Medications, or Psychosocial Aspects of Care
Weekly Objectives 3 and 4 are addressed in this discussion.

Before posting to the discussion board, locate one Clinical Best Practice Guideline or recent research article (within the past five years) related to sexuality, medications, or a psychosocial aspect of aging that aligns with your practice area or an area of interest.

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Then address the following:

Entitle your discussion post with the title of the article/guideline.
Provide a rationale for why you’ve chosen this article/guideline and state how you intend to use it in practice in one paragraph.
Apply one of the Recommended Baccalaureate Competencies and Curricular Guidelines for the Nursing Care of Older Adults that fit the article/guideline and state your rationale for using it. (Located in Appendix 2.A on page 30 of the textbook)
Attach the full research article or EBP guideline as a document in the discussion board so that other students can read it and respond more effectively.

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A Systematic Review of Practice Guidelines and Recommendations for Discontinuation of Cholinesterase Inhibitors in Dementia

The selected article is “A Systematic Review of Practice Guidelines and Recommendations for Discontinuation of Cholinesterase Inhibitors in Dementia” by Renn et al. (2018). Dementia is a grouping of social and thinking symptoms that disrupts how an individual goes about their daily functioning, which involves at least two brain impairment functions like poor judgment and memory loss (Livingston et al., 2020). In treating dementia, clinicians mainly introduce the patients to Cholinesterase inhibitors as the first-line pharmacological treatment for Alzheimer’s disease. Hence, the main reason for selecting the article is that it provides a clear guideline on discontinuing the use of Cholinesterase inhibitors due to their long-term use risks and effectiveness. Therefore, the article will be essential during practice since it provides the dos and don’ts, especially when dealing with Alzheimer’s patients under cholinesterase inhibitors, to balance its benefits and risks.

The article is more effective for Competency 2, which requires nursing students to serve as role models and advocates in providing quality care to the elderly. That is because the article provides effective knowledge and teaching and provides the national nursing practice guidelines on discontinuing Cholinesterase inhibitors using evidence-based research to ensure discontinuation effectiveness. Also, to discontinue Cholinesterase inhibitors effectively, these students need to learn how to engage in collaboration with other healthcare providers. For instance, the article by Renn et al. (2018) provides a systematic review of different books and articles on the most effective approach toward discontinuing Cholinesterase inhibitors. Through all the randomized trials that Renn et al. (2020) involved, the authors found that all guidelines did not offer any consensus on when and under what circumstances the discontinuation of Cholinesterase inhibitors should happen. That is because most textbooks and guidelines failed to respond or show the ineffectiveness of dementia’s progressive condition. Hence, when applying the discontinuation of Cholinesterase inhibitors, it is clear that nurses and other healthcare providers should focus more on an individualized approach when dealing with patients and their families, especially in making treatment decisions.

References

Livingston, G., Huntley, J., Sommerlad, A., Ames, D., Ballard, C., Banerjee, S., … & Mukadam, N. (2020). Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. The Lancet, 396(10248), 413-446. https://doi.org/10.1016/S0140-6736(20)30367-6

Renn, B. N., Asghar-Ali, A. A., Thielke, S., Catic, A., Martini, S. R., Mitchell, B. G., & Kunik, M. E. (2018). A systematic review of practice guidelines and recommendations for discontinuation of cholinesterase inhibitors in dementia. The American Journal of Geriatric Psychiatry, 26(2), 134-147. doi:10.1016/j.jagp.2017.09.027.