NURS-6630N Week 8

NURS-6630N Week 8 Sample

Therapy for Patients with Sleep/Wake Disorders

  1. In 3 or 4 sentences, explain the appropriate drug therapy for a patient who presents with MDD and a history of alcohol abuse. Which drugs are contraindicated, if any, and why? Be specific. What is the timeframe that the patient should see resolution of symptoms?

Care should be taken when treating patients with addiction and additional mental illness to avoid contraindications. The appropriate drug psychopharmacology for a person with major depressive disorder (MDD) and alcohol abuse is a combination of Acamprosate with escitalopram. Acamprosate reduces the effects of addiction while escitalopram is antidepressant. The medications are safe to use together (Donoghue et al., 2022). Antidepressants such as Bupropion are contraindicated in persons with comorbid alcohol abuse and MDD because of the risk of seizure or liver damage (Li et al., 2020).

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  1. List 4 predictors of late onset generalized anxiety disorder.
  • Low probability of remission
  • Higher severity and persistence
  • High risk of recurrence
  • Presence of comorbid mental disorders NURS-6630N Week 8
  1. List 4 potential neurobiology causes of psychotic major depression.
  • Hypersensitivity to stress
  • Electrical stimulation in the vagus nerve
  • Serotonin dysfunction
  • Electrical stimulation of the ventral striatum (Li et al., 2021)
  1. An episode of major depression is defined as a period of time lasting at least 2 weeks. List at least 5 symptoms required for the episode to occur
  • Depressed mood presenting in the form of sadness, hopelessness, or guilt
  • Diminished pleasure or interest in activities that a person once enjoyed (SAMHSA, 2020)
  • Weight loss or gain
  • Insomnia
  • Fatigue
  • Agitation
  • Diminished concentration
  1. List 3 classes of drugs, with a corresponding example for each class, that precipitate insomnia.
  • SSRI antidepressants example fluoxetine
  • Statins for example Lipitor
  • Stimulants for example Ritalin (Stokes et al., 2020)

NURS-6630N Week 8 References

Donoghue, K., Hermann, L., Brobbin, E., & Drummond, C. (2022). The rates and measurement of adherence to acamprosate in randomised controlled clinical trials: A systematic review. PlosOne, https://doi.org/10.1371/journal.pone.0263350.

Li, J., Wang, H., Li, M., Shen, Q., Li, X., Rong, X., & Peng, Y. (2020). Efficacy of pharmacotherapeutics for patients comorbid with alcohol use disorders and depressive symptoms-A bayesian network meta-analysis. CNS Neurosci Ther, 26(11),1185-1197. https://doi.10.1111/cns.13437.

Li, Z., Ruan, M., & Chen, J. (2021). Major Depressive Disorder: Advances in Neuroscience Research and Translational Applications. Neurosci. Bull, 37, 863–880. https://doi.org/10.1007/s12264-021-00638-3.

SAMHSA. (2020). Substance Use Disorder Treatment for People With Co-Occurring Disorders . Substance Abuse and Mental Health Services Administration.

Stokes, P., Jokinen, T., Amawi, S., Qureshi, M., Husain, M., Yatham, L., . . . Young, A. (2020). Pharmacological Treatment of Mood Disorders and Comorbid Addictions: A Systematic Review and Meta-Analysis. Can J Psychiatry, 65(11), 749-769. https://doi.10.1177/0706743720915420.

NURS-6630N Week 8

NURS-6630N: Week 8: Therapy for Patients With Sleep/Wake Disorders
Assignment 1: Short Answer Assessment. DUE 0N 7/24/22
As a psychiatric nurse practitioner, you will likely encounter patients who suffer from various mental health disorders. Not surprisingly, ensuring that your patients have the appropriate psychopharmacologic treatments will be essential for their overall health and well-being. The psychopharmacologic treatments you might recommend for patients may have potential impacts on other mental health conditions and, therefore, require additional consideration for positive patient outcomes. For this Assignment, you will review and apply your understanding of psychopharmacologic treatments for patients with multiple mental health disorders.
To Prepare
• Review the Learning Resources for this week.
• Reflect on the psychopharmacologic treatments that you have covered up to this point that may be available to treat patients with mental health disorders.
• Consider the potential effects these psychopharmacologic treatments may have on co-existing mental health conditions and/or their potential effects on your patient’s overall health.
To complete:
Address the following Short Answer prompts for your Assignment. Be sure to include references to the Learning Resources for this week.
1. In 3 or 4 sentences, explain the appropriate drug therapy for a patient who presents with MDD and a history of alcohol abuse. Which drugs are contraindicated, if any, and why? Be specific. What is the timeframe that the patient should see resolution of symptoms?
2. List 4 predictors of late onset generalized anxiety disorder.
3. List 4 potential neurobiology causes of psychotic major depression.
4. An episode of major depression is defined as a period of time lasting at least 2 weeks. List at least 5 symptoms required for the episode to occur. Be specific.
5. List 3 classes of drugs, with a corresponding example for each class, that precipitate insomnia. Be specific. NURS-6630N Week 8

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