The Different Levels of Translational Research Paper

The Different Levels of Translational Research Paper

 

The Different Levels of Translational Research

There are three levels of translational research: -T1- Basic research that is used to develop a new treatment or therapy. This research is conducted in a laboratory setting and aims to understand the fundamental biology behind a disease or condition. -T2- Preclinical research that is used to test the safety and efficacy of a new treatment or therapy in animals (Fort et al., 2017). This research is conducted in a laboratory setting and helps to determine if the treatment or therapy is safe and effective for humans. And -T3- Clinical trials that are used to test the safety and efficacy of a new treatment or therapy in humans. This research is conducted with patients who have the disease or condition being studied.

There are several ways in which translational research is different from evidence-based practice (EBP). The first has to do with the idea of “evidence.” In translational research, scientists strive to move discoveries made in the laboratory into practical applications that can be used in the real world. This means that the findings of translational research are based on sound scientific evidence. In contrast, EBP relies on a body of research that has been evaluated and found to be reliable (Parija, 2020). The goal of EBP is to use this existing body of knowledge to make informed decisions about patient care. Another difference between translational research and has to do with the time frame involved. Translational take longer time compared to EBP given the stages that has to be accomplished in the entire process.

Population health management (PHM) is the field of public health that concerns itself with the health and well-being of defined populations. It is a relatively new field, having been formally recognized only in the past few decades (Fort et al., 2017). PHM is built upon the foundation of translational research, which is the process of applying knowledge and findings from basic science research to practical applications in human health care. The goal of PHM is to improve population health by using knowledge gleaned from translational research to develop and implement interventions at the individual, community, and societal levels. Some common interventions employed by PHM practitioners include educational programs, screenings, targeted treatments, and policy changes.

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References

Fort, D. G., Herr, T. M., Shaw, P. L., Gutzman, K. E., &Starren, J. B. (2017). Mapping the evolving definitions of translational research. Journal of clinical and translational science, 1(1), 60-66.https://www.cambridge.org/core/journals/journal-of-clinical-and-translational-science/article/mapping-the-evolving-definitions-of-translational-research/39D2FB59ECC2F0C862E49E03E2403E12

Parija, S. C. (2020). Translational Research in Nursing… Vistas Galore.https://web.archive.org/web/20201212092716id_/https://pjn.sbvjournals.com/doi/pdf/10.5005/jp-journals-10084-12165

 

Identify the different levels of translational research. Explain how translational research is different from evidence-based practice and discuss application to population health management.